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Ethanol Sensitivity and Tolerance in Long-Term Memory Mutants of Drosophila melanogaster

Ethanol Sensitivity and Tolerance in Long-Term Memory Mutants of Drosophila melanogaster - Berger - 2008 - Alcoholism: Clinical and Experimental Research - Wiley Online Library

Mutants of the learning and/or memory pathways have differential responses to ethanol tolerance. Some mutants increased amnesia/learning loss, while others had an opposite effect to ethanol tolerance. Researchers tested a collection of 60 long-term memory mutants for 52 loci where these mutants limit learning so normal function of each mutation are thought to play into the long-term memory pathway. Researchers then ran an ethanol assay and quantified the ethanol tolerance of each mutant. The data suggests that these pathways overlap and suggest specific genes for each pathway.